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PhD Ed. Neuroscience: PHDC730 - Neuroscience: Brain Anatomy and Circuits

Course Description

The focus of the Neuroscience: Brain Anatomy and Circuits course is on concepts and mechanisms of neural function, beginning at the earliest cellular levels and expanding towards larger-scale brain function. Various aspects of cellular and molecular function, synaptic transmission, neural dynamics, mechanisms underlying cognition, and perceptual systems, are explored, along with their interactions at various levels to produce behavior. Multiple methodologies and approaches are used to address these issues and obtain a complete picture of brain function across these levels.

Articles

 Hodgkin, A. L., & Huxley, A. F. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology, 117(4), 500.

Lee, A., Fakler, B., Kaczmarek, L. K., & Isom, L. L. (2014). More than a pore: ion channel signaling complexes. Journal of Neuroscience, 34(46), 15159- 15169. https://doi.org/10.1523/JNEUROSCI.3275-14.2014

 Albright, T. D., Jessell, T. M., Kandel, E. R., & Posner, M. I. (2000). Neural science: a century of progress and the mysteries that remain. Neuron, 25(1), S1-S55. https://doi.org/10.1016/S0896-6273(00)80912-5

Vogel-Ciernia, A., & Wood, M. A. (2014). Neuron-specific chromatin remodeling: a missing link in epigenetic mechanisms underlying synaptic plasticity, memory, and intellectual disability disorders. Neuropharmacology, 80, 18-27. https://doi.org/0.1016/j.neuropharm.2013.10.002

Bender, A. R., Keresztes, A., Bodammer, N. C., Shing, Y. L., Werkle‐Bergner, M., Daugherty, A. M., ... & Raz, N. (2018). Optimization and validation of automated hippocampal subfield segmentation across the lifespan. Human brain mapping, 39(2), 916-931. https://doi.org/ 10.1016/j.neuroimage.2018.05.070

Hosch, E. (1973). Natural Categories. Cognitive Psychology 4, 328-350

Bellmund, J. L., Gärdenfors, P., Moser, E. I., & Doeller, C. F. (2018). Navigating cognition: Spatial codes for human thinking. Science, 362(6415). https://doi.org/10.1126/science.aat6766

Vo, V. A., Sprague, T. C., & Serences, J. T. (2017). Spatial tuning shifts increase the discriminability and fidelity of population codes in visual cortex. Journal of Neuroscience, 37(12), 3386-3401. https://doi.org/10.1523/JNEUROSCI.3484-16.2017 

Epstein, R. A., Patai, E. Z., Julian, J. B., & Spiers, H. J. (2017). The cognitive map in humans: spatial navigation and beyond. Nature neuroscience, 20(11), 1504. https://doi.org/10.1371/journal.pcbi.1007430

Melzack, R. (2008). The future of pain. Nature Reviews Drug Discovery, 7(8), 629-629. https://doi.org/10.1038/nrd2640

Carreiras, M., Armstrong, B. C., Perea, M., & Frost, R. (2014). The what, when, where, and how of visual word recognition. Trends in cognitive sciences, 18(2), 90-98. https://doi.org/10.1016/j.tics.2013.11.005 

Goodale MA, Milner AD (1992). Separate visual pathways for perception and action. Trends in Neuroscience. 15 (1), 20–25. https://doi.org/10.1016/0166-2236(92)90344-8

Vinje, W., and J Gallant. (2000). Sparse Coding and Decorrelation in Primary Visual Cortex during Natural Vision. Science, 287, 1273-1276. https://doi.org/10.1126/science.287.5456.1273

Itti, L., & Koch, C. (2001). Computational modelling of visual attention. Nature reviews neuroscience, 2(3), 194-203. https://doi.org/10.1038/35058500 

Maguire, E. A., Gadian, D. G., Johnsrude, I. S., Good, C. D., Ashburner, J., Frackowiak, R. S., & Frith, C. D. (2000). Navigation-related structural change in the hippocampi of taxi drivers. Proceedings of the National Academy of Sciences, 97(8), 4398-4403. https://doi.org/10.1073/pnas.070039597

Murthy, V. N. (2011). Olfactory maps in the brain. Annual review of neuroscience, 34, 233-258. https://doi.org/10.1146/annurev-neuro-061010-113738 

Rolls, E. T. (2015). Taste, olfactory, and food reward value processing in the brain. Progress in neurobiology, 127, 64-90. https://doi.org/10.1016/j.pneurobio.2015.03.002

Brand, A., O. Behrend, T. Marquardt, D. McAlpine, and B. Grothe. (2002). Precise inhibition is essential for microsecond interaural time difference coding. Nature, 417, 543-547. https://doi.org/10.1038/417543a

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